✦ LIBER ✦

Dynamics of hydrogen bonding and energy transfer in matrix-assisted laser desorption

✍ Scribed by Akos Bencsura; Akos Vertes

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 486 KB
Volume: 247
Category: Article
ISSN: 0009-2614
DOI: 10.1016/0009-2614(95)01179-1

No coin nor oath required. For personal study only.

✦ Synopsis

A molecular dynamics simulation of matrix-assisted laser desorption is presented for host and guest particles with internal structure. The laser-induced phase transition is modeled in a hemispherical volume of pyridine-3-carboxylic acid matrix seeded with a leucine enkephalin guest molecule. Following an instantaneous temperature jump to 1500 K, representing the laser excitation, the network of hydrogen bonds is disrupted in approximately 3 ps. After a 0.7 ps segregation period, the guest molecule is entrained by the evaporating matrix molecules. The guest lift-off velocity is estimated at = 156 m/s, a value about a factor of two lower than measured for neutral matrix molecules in similar systems.

📜 SIMILAR VOLUMES

Matrix–Guest Energy Transfer in Matrix-a

Matrix–Guest Energy Transfer in Matrix-assisted Laser Desorption

✍ Akos Bencsura; Vivek Navale; Mehrnoosh Sadeghi; Akos Vertes 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 1 views

Molecular dynamics was used to analzye energy transfer rates between matrix and guest molecules in matrix-assisted laser desorption allowing for a large number of internal degrees of freedom. The effect of initial matrix temperature jump on internal energy equilibration times and on guest limiting t

Internal energy build-up in matrix-assis

Internal energy build-up in matrix-assisted laser desorption/ionization

✍ Valérie Gabelica; Eric Schulz; Michael Karas 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 329 KB

This paper reports detailed studies on the internal energy of ions formed in matrix-assisted laser desorption/ionization (MALDI) using delayed extraction MALDI-time-of-flight (TOF) and atmospheric pressure (AP) MALDI mass spectrometric (MS) methods. We use benzylpyridinium cations as internal energy

H-atom transfer following analyte photoi

H-atom transfer following analyte photoionization in matrix-assisted laser desorption/ionization processes

✍ P. J. Calba; J. F. Muller; M. Inouye 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 72 KB 👁 1 views

## As recently shown in Fourier transform ion cyclotron resonance mass spectrometry studies (Rapid Commun. Mass Spectrom. 11, 1602, 1997), photochromic systems can be used as molecular probe for the study of matrix-assited laser desorption ionization (MALDI) processes inducing the typical formatio

Ionization Modelling of Matrix Molecules

Ionization Modelling of Matrix Molecules in Ultraviolet Matrix-assisted Laser Desorption/Ionization

✍ D. A. Allwood; P. E. Dyer; R. W. Dreyfus 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB 👁 2 views

A scheme of matrix ionization in UV matrix-assisted laser desorptiodionization is presented. Excitation to an upper lying electronic singlet state by the absorption of two photons and subsequent thermionic emission by vibronic coupling is proposed as the primary route for the formation of unprotonat

Insight into absorption of radiation/ene

Insight into absorption of radiation/energy transfer in infrared matrix-assisted laser desorption/ionization: the roles of matrices, water and metal substrates†

✍ Victor L. Talrose; Maria D. Person; Randy M. Whittal; Fred C. Walls; Alma L. Bur 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB 👁 2 views

Although the ionization/desorption mechanisms in matrix-assisted laser desorption/ionization (MALDI) remain poorly understood, there is a clear difference between the energy absorption processes in the ultraviolet (UV) and infrared (IR) modes of operation. UV-MALDI demands an on-resonance electronic

Determination of disulfide bonds in high

Determination of disulfide bonds in highly bridged α-dendrotoxin by matrix-assisted laser desorption/ionization mass spectrometry

✍ Hélène Belva; Chrystel Valois; Catherine Lange 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

A methodology which combines tryptic digestions, 1,4-dithiothreitol reduction, and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF-MS) allows verification of the location of the disulfide bridges in alpha-dendrotoxin (C7-C57, C16-C40 and C32-C53). Copyright 2000 John Wiley &