The time-resolved transmission of collagen films and 10-pm sections of bovine cornea during ArF laser ablation has been investigated. The film studies were performed on thin layers of extracted bovine corneal collagen, the principal chromophore in 193 nm photoablation. Transmission measurements were
Dynamics of ablation plume particles generated during excimer laser corneal ablation
β Scribed by D. W. Hahn; M. N. Ediger; G. H. Pettit
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 546 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0196-8092
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β¦ Synopsis
Background and Objective: Although the empirical characteristics of ArF excimer laser corneal ablation have been well documented, the exact ablation mechanisms are not well understood. The present paper reports a quantitative analysis of corneal ablation plumes using in situ time resolved laser light scattering and Raman spectroscopy. Study DesignlMateriaZs and Methods: Bovine corneas were used as the ArF excimer laser ablation targets. Light scattering data were recorded from the ablation plume as a function of height above the tissue surface and as function of delay time with respect to the ablative ArF laser pulse. Results: Raman spectra of the ablation plume allow identification of the particles as water. Mean plume particle diameters are found to decrease with height, while the particle volume fractions are relatively constant. The total volume of plume particles correlates well with the total volume of water in the ablated corneal tissue.
ConcZusion:
The finding of a non-evolving plume composed of water spherules, combined with the excellent agreement between total volume of water in the plume and the content of water in the ablated corneal tissue, support the concept of photodecomposition or "cold ablation" for corneal tissue during ArF excimer laser ablation.
π SIMILAR VOLUMES
Transient changes in the transmission of a 355 nm probe pulse through corneal tissue during 193 nm ArF laser ablation have been examined. A significant decrease in collimated transmission of the probe beam was observed for time delays between 10 ns and 1 ms after the 193 nm laser pulse. At 10 ns del
Pulse-to-pulse consistency of excimer laser etching of cornea has been examined via two noncontact techniques: photoacoustic probe beam deflection, and time-resolved excimer pulse reflectometry. These methods clearly document the incubation phenomenon accompanying excimer laser ablation of polymethy
## Abstract ## Background and Objective The goal of the present work is to assess whether bovine corneal ablations generated at laser repetition rates of up to 400 Hz are comparable to ablations performed at rates consistent with current clinical laser systems. ## Study Design/Materials and Metho