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Dynamic Optimization of Fed-Batch Bioreactors Using the Ant Algorithm

โœ Scribed by V. K. Jayaraman; B. D. Kulkarni; Kapil Gupta; J. Rajesh; H. S. Kusumaker

Book ID
109386195
Publisher
American Institute of Chemical Engineers
Year
2001
Tongue
English
Weight
78 KB
Volume
17
Category
Article
ISSN
8756-7938

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This study addressed the problem of maximizing cell mass and monoclonal antibody production from a fed-batch hybridoma cell culture. We hypothesized that inaccuracies in the process model limited the mathematical optimization. On the basis of shaker flask data, we established a simple phenomenologic