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Dynamic Force Spectroscopy of Glycoprotein Ib-IX and von Willebrand Factor

✍ Scribed by Arya, Maneesh; Kolomeisky, Anatoly B.; Romo, Gabriel M.; Cruz, Miguel A.; López, José A.; Anvari, Bahman

Book ID
119918842
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
275 KB
Volume
88
Category
Article
ISSN
0006-3495

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## Background and objective: Thrombus formation is initiated by adhesion of the platelet receptor, glycoprotein (gp) ib-ix-v complex, to its adhesive ligand, von willebrand factor (vwf), in the subendothelium or plasma. the vwf-binding domain of gp ib-ix-v is in the gp ibalpha subunit of the comple