## Abstract Histones are now regarded as integral and dynamic components of the machinery responsible for regulating gene transcription. Many types of cancer and other diseases are associated with translocations or mutations in chromatinβmodifying enzymes and regulatory proteins. Much of the work i
β¦ LIBER β¦
Dynamic distribution of Ser-10 phosphorylated histone H3 in cytoplasm of MCF-7 and CHO cells during mitosis
β Scribed by LI, Deng Wen; YANG, Qin; CHEN, Jia Tong; ZHOU, Hao; LIU, Ru Ming; HUANG, Xi Tai
- Book ID
- 110020621
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 277 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0007-0610
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## Phosphorylation of histone H3 (H3) on Ser-10 correlates with chromatin condensation at mitosis. A new monoclonal antibody (anti-H3-P) was developed that recognizes phosphorylated H3 (H3-P). This antibody was used in multiparameter flow cytometric analysis to relate H3 phosphorylation in individua