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Dynamic contrast enhanced perfusion MRI in mycosis fungoides

✍ Scribed by Meng Law; Noah Teicher; David Zagzag; Edmond A. Knopp

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
897 KB
Volume
18
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Mycosis fungoides is a malignant, cutaneous lymphoma of T‐helper (TH or CD4+) cells. At presentation, the disease is usually limited to the skin, with lesions that resemble eczema or psoriasis. Neurologic involvement is uncommon. This case demonstrates the conventional MRI and dynamic contrast enhanced perfusion MRI findings in intracerebral mycosis fungoides. T1‐weighted spin echo imaging demonstrated a lesion with slightly decreased signal within the body of the corpus callosum. The lesion was isointense with grey matter on axial T2‐weighted imaging. Following administration of contrast, there was patchy heterogeneous enhancement. Multiple relative cerebral blood volume (rCBV) measurements were made and the minimum rCBV was 0.30 with the maximum rCBV being 1.61. The mean rCBV was 0.81 ± 0.49 (average of 10 measurements and standard deviation). J. Magn. Reson. Imaging 2003;18:364–367. © 2003 Wiley‐Liss, Inc.

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