✦ LIBER ✦

Dynamic adhesion and separation of cells in vitro II. Interactions of cells with hydrophilic and hydrophobic surfaces

✍ Scribed by Leonard Weiss; Leslie E. Blumenson

Publisher: John Wiley and Sons
Year: 1967
Tongue: English
Weight: 886 KB
Volume: 70
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040700104

No coin nor oath required. For personal study only.

✦ Synopsis

Experiments made on the passage of cells through untreated and siliconized glass beads, and on the adhesion and spread of cultured cells on glass and Teflon surfaces show that, i n the absence of serum and in its presence in low concentrations, cell adhesion and spread is sensitive to substratum wettability. On the other hand, in the presence of 100% serum, no differences in adhesive parameters are detectable. It is concluded that arguments correlating cell adhesion to surface wettability, and, by inference, surface free energy, are unsubstantiated in 100% serum, which may well approximate to the i n vivo situation.

The results also show no correlation between parameters of cell adhesion and cell separation, and thereby support the hypothesis that these are different processes.

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