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Dynactin is essential for growth cone advance

✍ Scribed by Takako K. Abe; Takao Honda; Kohtaro Takei; Katsuhiko Mikoshiba; Diane Hoffman-Kim; Daniel G. Jay; Ryozo Kuwano

Book ID
116296847
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
705 KB
Volume
372
Category
Article
ISSN
0006-291X

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## Abstract This study evaluated somatic and dendritic growth of neurons in the frontoparietal cortex of __Igf1__–/– brains. Pyramidal neuron density was increased by ∼25% (__P__ = .005) and soma size reduced by ∼10% (__P__ < .001). Golgi staining revealed that cortical layer II–III neurons exhibit