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Dual Role of Protein Phosphorylation in DNA Activator/Coactivator Binding

โœ Scribed by Dadarlat, Voichita M.; Skeel, Robert D.


Book ID
119207695
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
544 KB
Volume
100
Category
Article
ISSN
0006-3495

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Inducible phosphorylation or dephosphorylation of transcription factors is an important mechanism of signal-dependent gene regulation in eukaryotic cells. This paper describes a combination of techniques that can be used to study the effect of this covalent protein modification on the DNA-binding ac