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Dual HER2-targeted approaches in HER2-positive breast cancer

โœ Scribed by Eugene R. Ahn; Charles L. Vogel

Publisher
Springer US
Year
2011
Tongue
English
Weight
520 KB
Volume
131
Category
Article
ISSN
0167-6806

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## Abstract Chromosomal instability (CIN) is a common cause of tumour heterogeneity and poor prognosis in solid tumours and describes cellโ€“cell variation in chromosome structure or number across a tumour population. In this article we consider evidence suggesting that CIN may be targeted and may in