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Dual-color fluorescence in situ hybridization for detecting the t(x;18)(p11.2;q11.2) associated with synovial sarcoma in inter-phase and metaphase nuclei

✍ Scribed by S. Li; J.G. Lucas; K.S. Theil


Book ID
114136723
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
143 KB
Volume
98
Category
Article
ISSN
0165-4608

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Identification of the t(X;18)(p11.2;q11.2) and the fusion gene products, SYT-SSX1 and SYT-SSX2, associated with a high proportion of synovial sarcomas, has been shown to be a useful diagnostic aid. This study demonstrates the application of dual colour fluorescence in situ hybridization to paraffin-