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Drugs of Abuse Volume 79 || From Drugs of Abuse to Parkinsonism: The MPTP Mouse Model of Parkinson's Disease

✍ Scribed by Wang, John Q.

Book ID
115522965
Publisher
Humana Press
Year
2002
Weight
211 KB
Category
Article
ISBN-13
9781592593583

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o