This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.
✦ LIBER ✦
Drug–antibody conjugates with anti-HIV activity
✍ Scribed by Mark Paulik; Paul Grieco; Chinpal Kim; Hans-Günther Maxeiner; Hans-Peter Grunert; Heinz Zeichhardt; Dorothy M Morré; D.James Morré
- Book ID
- 113994603
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 571 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0006-2952
No coin nor oath required. For personal study only.
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## Abstract As an approach to developing more specific anti‐tumour therapeutic agents, daunomycin has been covalently linked to the human tumour localizing, murine monoclonal antibody 79IT/36. Four procedures for coupling drug to antibody were investigated. The sugar amino group of daunomycin was m