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Drug synergism of antihypertensive action in combination of telmisartan with lercanidipine in spontaneous hypertensive rats

โœ Scribed by Jung-Jin Lee; Chang-Yong Shin; Hong-Joon Park; Wei-Yun Zhang; Yohan Kim; In-Su Kim; Kyu-Hyun Lee; Chang-Seon Myung

Publisher
Springer
Year
2010
Tongue
English
Weight
389 KB
Volume
33
Category
Article
ISSN
0253-6269

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Antihypertensive effect of roselle (Hibiscus sabdariffa) calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in Wistar rats
โœ P. C. Onyenekwe; E. O. Ajani; D. A. Ameh; K. S. Gamaniel ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 109 KB ๐Ÿ‘ 2 views

The LD 50 of roselle calyx extract and its eect on blood pressure were determined. The LD 50 was found to be above 5000 mg kg ร€1 . Roselle calyx infusion was found to lower signiยฎcantly ( p 5 0 . 05) both systolic and diastolic pressure in spontaneously hypertensive and normotensive WistarยฑKyoto rat