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Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib

✍ Scribed by Haouala, A.; Widmer, N.; Duchosal, M. A.; Montemurro, M.; Buclin, T.; Decosterd, L. A.


Book ID
111901355
Publisher
American Society of Hematology
Year
2011
Tongue
English
Weight
103 KB
Volume
117
Category
Article
ISSN
0006-4971

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The BCR/ABL-inhibitors imatinib, nilotin
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## Abstract In chronic myeloid leukemia (CML), BCR/ABL‐mediated oncogenic signaling can be targeted with the BCR/ABL‐inhibitors Imatinib, Nilotinib and Dasatinib. However, these agents may also affect anti‐tumor immunity. Here, we analyzed the effects of the 3 BCR/ABL‐inhibitors on natural killer (