Drug interaction of herbal tea containing St. John's wort with cyclosporine
β Scribed by Dominik Mark Alscher; Ulrich Klotz
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 139 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0934-0874
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract St. John's wort, a popular herbal remedy for depression, is known to interact with many Western drugs because of the ability of its components to induce liver enzymes. Lower concentrations of various drugs due to increased clearance have been reported. Because immunoassays are commonly
## Abstract Concomitant administration of botanical supplements with drugs that are Pβglycoprotein (Pβgp) substrates may produce clinically significant herbβdrug interactions. This study evaluated the effects of St. John's wort and __Echinacea__ on the pharmacokinetics of digoxin, a recognized Pβgp
## Abstract Cytochrome P450 2D6 (CYP2D6), an important CYP isoform with regard to drugβdrug interactions, accounts for the metabolism of βΌοΈ30% of all medications. To date, few studies have assessed the effects of botanical supplementation on human CYP2D6 activity __in vivo__. Six botanical extracts