Gauging the clinical significance of P-g
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Bill J. Gurley; Ashley Swain; D. Keith Williams; Gary Barone; Sunil K. Battu
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Article
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2008
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John Wiley and Sons
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English
⚖ 421 KB
## Abstract Concomitant administration of botanical supplements with drugs that are P‐glycoprotein (P‐gp) substrates may produce clinically significant herb‐drug interactions. This study evaluated the effects of St. John's wort and __Echinacea__ on the pharmacokinetics of digoxin, a recognized P‐gp