Drug hydroxylator phenotype in Hungary
✍ Scribed by I. Szórády; A. Sánta
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 112 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Hydroxylation at C-3' of doxorubicin (DOX) yields the uncharged congener hydroxyrubicin, which circumvents P-glycoprotein-mediated drug resistance without loss of topoisomerase II inhibitory activity. Hydroxyrubicin-resistant cells exhibit a phenotype that is uniquely different from DOX resistance b
## S-Mephenytoin hydroxylation phenotypes in a Jordanian population We tested the ability of 194 unrelated, healthy Jordanian volunteers to metabolize Smephenytoin. Mephenytoin (100 mg) was coadmmistered with debrisoquin (10 mg) orally and urine was collected for 8 hours. Mephenytoin metabolism wa