Drug Development-targeted Screening of Leptin Agonist Glycopeptides
β Scribed by Daniel Knappe; Laszlo Otvos; Francesco De Pascali; Marco Cassone; Laura Scolaro; Giovanni Abbadessa; Cynthia Carrillo-Infante; Mohammad F. Kiani; Fred Donelson; Ralf Hoffmann; Eva Surmacz
- Book ID
- 106452197
- Publisher
- Springer Netherlands
- Year
- 2008
- Tongue
- English
- Weight
- 276 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1573-3149
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In this article C . L. Tsou, of the Institute of Biophysics, Beijing, criticizes the use of the expression I,,, the inhibitor concentration to produce 50% inhibition of a particular enzyme as a 'most unfortunate' parameter, when screening enzyme inhibitors designed as drugs. Comments on Dr Tsou's po
The purpose of these studies was to determine the levels of intrinsic activity in vitro at muscarinic receptor pharmacological subtypes (M 1 , M 2 , and M 3 ) that would optimize cognitive activity while minimizing acute adverse cholinergic effects in vivo. These levels of intrinsic efficacy at M 1