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Drug analysis by continuously monitored liquid chromatography/mass spectrometry with a quadrupole mass spectrometer

✍ Scribed by Henion, Jack D.

Book ID
120270115
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
631 KB
Volume
50
Category
Article
ISSN
0003-2700

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The pattern of nuclease degradation observed for an antisense phosphorothioate oligonucleotide in pig kidney was determined using liquid chromatography/electrospray mass spectrometry (LC/ESI-MS) and LC/ESI-MS/MS with a quadrupole ion trap mass spectrometer. Metabolites were separated by length using