Drug absorption VIII: Kinetics of GI absorption of methotrexate
โ Scribed by Vinod S. Chungi; David W. A. Bourne; Lewis W. Dittert
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 221 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
By using the GI tube technique, niacin was shown to be equally well absorbed from the stomach and the upper small intestine. The maximum plasma niacin concentrations occurred 10-20 and 5-10 min, respectively, after instillation. Thus, the physiological prerequisites for a physically retarded niacin
longer periods, the rate of absorption of salicylic acid was found to be much slower (see Fig. 6). This has lead us to study the influence of fasting on drug absorption rates, and the results of that study are to be reported separately (18). Future publications will deal with the influence of the p