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Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma

โœ Scribed by Chan, Agnes Sze Wah; Tsui, Wai Yin; Chen, Xin; Chu, Kent Man; Chan, Tsun Leung; Chan, Annie Shuk Yee; Li, Rui; So, Samuel; Yuen, Siu Tsan; Leung, Suet Yi

Book ID
110067886
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
536 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract The retinoblastoma proteinโ€interacting zinc finger gene, __RIZ1__ (GenBank accession number U17838), is involved in chromatinโ€mediated gene expression and is also a target for frameshift mutation in microsatelliteโ€unstable cancers. Methylation of the __RIZ1__ promoter CpG island has bee