Downregulation of the c-MYC target gene,
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Pablo E. Vivas-Mejía; Bulent Ozpolat; Xian Chen; Gabriel Lopez-Berestein
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Article
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2009
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John Wiley and Sons
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French
⚖ 484 KB
## Abstract Arsenic trioxide (ATO) induces differentiation and apoptosis in acute promyelocytic leukemia (APL). Several reports indicate that in APL cells apoptosis occurs mainly by a mechanism that involves the inhibition of glutathione peroxidase, one of the enzymes that regulates mitochondrial l