## Abstract Typical and atypical antipsychotic drugs, though both effective, act on different neurotransmitter receptors and are dissimilar in some clinical effects and side effects. The typical antipsychotic drug haloperidol has been shown to cause a decrease in the expression of brainβderived neu
Downregulation of brain-derived neurotrophic factor mRNA in adult rat brain after acute administration of methylmercury
β Scribed by Helena Andersson; Eva Lindqvist; Lars Olson
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 1017 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1044-7393
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Levels of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) mRNA expression were measured in a rodent model of traumatic brain injury (TBI) following unilateral injury to the cerebral cortex. To obtain reliable data on the co-expression of neurotrophin genes, adjacent coronal section
Expression of neurotrophins in pure microglia cultured from embryonic rat brain and the effects of lipopolysaccharide (LPS) on the expression were investigated. In untreated cultures, nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin (NT)-4/5 mRNAs were detected b