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Down syndrome and leukemia: unusual clinical aspects and unexpected methotrexate sensitivity

โœ Scribed by M. Peeters; A. Poon


Book ID
104776985
Publisher
Springer
Year
1987
Tongue
English
Weight
999 KB
Volume
146
Category
Article
ISSN
0340-6997

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Of 2947 children with acute lymphocytic leukemia (ALL), treated during three consecutive studies of the Pediatric Oncology Group (1974-1986), 52 (1.8%) had Down's Syndrome (DS). Comparison of clinical and laboratory characteristics showed no significant differences in leukocyte count, racial distrib