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Down-Regulation of Stat3 Decreases Invasion Activity and Induces Apoptosis of Human Glioma Cells

โœ Scribed by Fuxue Chen; Yaming Xu; Youqun Luo; Da Zheng; Yichao Song; Kangkang Yu; Hong Li; Li Zhang; Weiwei Zhong; Yonghua Ji


Book ID
107575276
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
360 KB
Volume
40
Category
Article
ISSN
0895-8696

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We have reported high expression of CD44H in human glioma cells. To investigate the role of CD44H in the invasion of human glioma, we established a CD44-anti-sense-gene-expression glioma cell line named U-251AI. The expression of CD44H in the G-4 18-selected U-25 I A l cells was reduced to 2096 of t