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Down-regulation of interleukin-1β production and PGE2 accumulation by an indomethacin-phenylalanine derivative in human monocytes

✍ Scribed by Patrick Poyet; Florence Doualla-Bell; Dominique Lévesque; Nathalie Ritchot; Jean-Martin Guay; François Marceau; René C.-Gaudreault

Book ID
117175711
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
597 KB
Volume
62
Category
Article
ISSN
0024-3205

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✍ Urszula Orlinska; Robert C. Newton 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 872 KB

## Abstract When monocytes are activated with endotoxin (lipopolysaccharide [LPS]), they make and release several mediators, including interleukin‐1β (IL‐1β). This study was undertaken to investigate the role of glucose in IL‐1β production by these cells. IL‐1β was produced in a dose‐dependent mann