Down-regulation of Hsp27 radiosensitizes human prostate cancer cells
β Scribed by SHAHRAM TEIMOURIAN; RAZIEH JALAL; MOSTAFA SOHRABPOUR; BAHRAM GOLIAEI
- Book ID
- 108977190
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 145 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0919-8172
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p27 Kip1 is a cyclin-dependent kinase inhibitor whose down-regulation has been observed in several tumour models, including breast, colorectal, and gastric carcinomas. The purpose of this study was to assess p27 Kip1 protein expression in normal and benign prostatic epithelia as well as the possible
## Abstract Storeβoperated Ca^2+^ channels control homeostasis between extracellular Ca^2+^ reservoir and intracellular Ca^2+^ storage and play important roles in apoptosis in a wide variety of cells, including prostate epithelia. Recent studies have shown that the acquired apoptosisβresistant natu