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Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells

✍ Scribed by Mohanam, Sanjeeva; Jasti, Sushma L; Kondraganti, Sudha R; Chandrasekar, Nirmala; Lakka, Sajani S; Kin, Yoshiaki; Fuller, Gregory N; Yung, Alfred WK; Kyritsis, Anthanassios P; Dinh, Dzung H

Book ID
110064755
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
403 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract The __RB18A/MED1__ human gene, also named __TRAP220__, __DRIP205__ and __PBP__, encodes for a single 205 kDa component, which interacts with nuclear receptors and transcription factors. RB18A/MED1 chromosome localization on locus 17q12‐q21.1 suggests its involvement in human cancers. We