Sulindac and its metabolites inhibit inv
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Hyung-Chahn Lee; In-Chul Park; Myung-Jin Park; Sungkwan An; Sang-Hyeok Woo; Hyeo
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Article
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2005
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John Wiley and Sons
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English
⚖ 332 KB
## Abstract Non‐steroidal anti‐inflammatory drug (NSAID), sulindac has chemopreventive and anti‐tumorigenic properties, however, the molecular mechanism of this inhibitory action has not been clearly defined. The Akt/protein kinase B, serine/threonine kinase is well known as an important mediator o