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Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer

✍ Scribed by Yang, Hongjian; He, Xiangming; Zheng, Yabing; Feng, Weiliang; Xia, Xianghou; Yu, Xingfei; Lin, Zhiqiang

Book ID: 121754528
Publisher: John Wiley and Sons
Year: 2014
Tongue: English
Weight: 909 KB
Volume: 84
Category: Article
ISSN: 1747-0277
DOI: 10.1111/cbdd.12348

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## Abstract Breast cancer (BC) is the leading cancer in the world in terms of incidence and mortality in women. However, the mechanism by which BC develops remains largely unknown. The increase in cytosolic free Ca^2+^ can result in different physiological changes including cell growth and death. O