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Down regulation of angiogenesis antagonist EFEMP1 is associated with unfavourable prognosis in sporadic breast cancer patients

✍ Scribed by J. Ramser; N. Harbeck; A. Sadr-Nabavi; J. Naehrig; R. Busch; M. Kiechle; A. Meindl


Book ID
119597842
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
70 KB
Volume
6
Category
Article
ISSN
1359-6349

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## Abstract EGF‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) was recently described as an antagonist of angiogenesis. Motivated by a strong dependence of tumor growth and metastasis on angiogenesis, we investigated the role of EFEMP1 in human breast cancer. We applied RNA microar