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Double-stranded deoxyribonucleic acid binds to HLA class II molecules and inhibits HLA class II-mediated antigen presentation

โœ Scribed by Gilberto Filaci; Paola Contini; Iolanda Grasso; Donatella Bignardi; Massimo Ghio; Lorella Lanza; Marco Scudeletti; Francesco Puppo; Martino Bolognesi; Roberto S. Accolla; Francesco Indiveri


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
197 KB
Volume
28
Category
Article
ISSN
0014-2980

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Signal transduction via HLA class-ll antigens has been studied using human resting B lymphocytes and monoclonal anti-HLA class-ll antibodies. An increased intracellular calcium flux, phosphatidylinositol biphosphate hydrolysis and activation of protein kinase C have all been observed following signa