𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation

✍ Scribed by Geier, Martina; Braun, Andreas; Fladischer, Patrik; Stepniak, Piotr; Rudroff, Florian; Hametner, Christian; Mihovilovic, Marko D.; Glieder, Anton

Book ID
120162582
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
414 KB
Volume
280
Category
Article
ISSN
1432-1327

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Recombinant Production of Human Microsom
Recombinant Production of Human Microsomal Cytochrome P450 2D6 in the Methylotrophic Yeast Pichia pastoris
✍ Matthias Dietrich; Lisa Grundmann; Katja Kurr; Laura Valinotto; Tanja Saussele; πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 223 KB πŸ‘ 1 views

## Abstract __Microsomal cytochrome P450 monooxygenases of groups 1–3 are mainly expressed in the liver and play a crucial role in phase 1 reactions of xenobiotic metabolism. The cDNAs encoding human CYP2D6 and human NADPH‐P450 oxidoreductase (CPR) were transformed into the methylotrophic yeast__ P