Double Philadelphia-chromosome: a resistance factor on the imatinib mesylate therapy for chronic myeloid leukemia
β Scribed by L. Otero; M. H Ornellas; J. Dobbin; T. De Souza Fernandez
- Book ID
- 111415042
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 52 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1751-5521
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π SIMILAR VOLUMES
## Abstract ## BACKGROUND Older age is a consistent poor prognostic factor in patients with Philadelphia chromosome (Ph)βpositive chronic myelogenous leukemia (CML). Whether this is related to an intrinsic worse disease biology or to inadequate drug delivery or excessive treatmentβassociated toxic
## Abstract ## BACKGROUND The effect on prognosis of adding imatinib mesylate to the treatment of patients with Philadelphia chromosome (Ph)βpositive chronic myelogenous leukemia (CML) has not been explored fully. The objective of the current study was to evaluate the benefit of adding imatinib to