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Additional rearrangements affecting the derivative chromosome 9 involved in the standard Philadelphia translocation after imatinib therapy in a patient with chronic myeloid leukemia

✍ Scribed by Huan-Ping Wang; Zhi-Mei Chen; Ji-Yu Lou; Huan Xu; Yun-Biao Yu; Jie Jin


Book ID
113513300
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
551 KB
Volume
182
Category
Article
ISSN
0165-4608

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## Abstract We report a case of __BCR‐ABL__‐negative atypical chronic myeloid leukemia (CML) with translocation t(4;22) (q12;q11.2) juxtaposing the breakpoint cluster region (__BCR__) and platelet‐derived growth factor receptor–alpha (__PDGFRA__) genes. The patient was a 57‐year‐old man with a hist