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Double minutes containing amplified bcr-abl fusion gene in a case of chronic myeloid leukemia treated by imatinib

✍ Scribed by Frédéric Morel; Marie-Josée Le Bris; Angèle Herry; Geneviève Le Calvez; Véronique Marion; Jean-François Abgrall; Christian Berthou; Marc De Braekeleer


Book ID
114423209
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
127 KB
Volume
70
Category
Article
ISSN
0902-4441

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Integration of amplified BCR/ABL fusion
✍ Simone Metzke-Heidemann; Lana Harder; Stefan Gesk; Robert Schoch; Stefan Jenisch 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract We describe the cases of two patients with Philadelphia chromosome–positive chronic myeloid leukemia (CML), in whom the extramedullary blastic phase developed during disease progression. The similar clinical presentations of these patients was accompanied by gain of identical secondary