Double Asymmetric Induction in Intramolecular C-H Insertion Reactions of α -Diazo β -Keto Esters
✍ Scribed by Hashimoto, Shun-ichi; Watanabe, Nobuhide; Kawano, Katsuhiro; Ikegami, Shiro
- Book ID
- 120412357
- Publisher
- Taylor and Francis Group
- Year
- 1994
- Tongue
- English
- Weight
- 476 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0039-7911
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## Abstract For Abstract see ChemInform Abstract in Full Text.
A highly functionalized cyclopentanone building block 13 was prepared by a facile Rh-catalyzed intramolecular C H insertion reaction of an enantiopure a-diazo-g-hydroxy-b-ketosulfone 12, in turn derived from an a-hydroxy acid 2. A cyclic g-hydroxy vinyl sulfone 16 was also prepared from 13.
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