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Dose-Response Assessments for Developmental Toxicity: IV. Benchmark Doses for Fetal Weight Changes

✍ Scribed by Robert J. Kavlock; Bruce C. Allen; Elaine M. Faustman; Carole A. Kimmel

Book ID
115608478
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
628 KB
Volume
26
Category
Article
ISSN
0272-0590

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✍ JAMES J. CHEN; DAVID W. GAYLOR; JAMES B. LABORDE πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 662 KB

A biologically-based dose-response model for predicting developmental malformation effects from exposure to a toxic substance during pregnancy is developed. The biological basis of this model arises from the expectation of exponential growth in rodents during gestation, and the exponential growth ra