## Abstract The doseโdependent pharmacokinetic parameters of a new neuroprotective agent for ischemiaโreperfusion damage, KRโ31378, were evaluated after intravenous and oral administration, 10, 20, and 50 mg/kg, to rats. After intravenous administration of 50 mg/kg, the doseโnormalized (10 mg/kg) A
Dose-dependent pharmacokinetic study of pefloxacin, a new antibacterial agent, in humans
โ Scribed by J. Barre; G. Houin; J. P. Tillement
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 334 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0022-3549
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## Abstract The doseโdependency of the pharmacokinetics of a new Na^+^/H^+^ exchanger inhibitor, KRโ33028 was evaluated in rats after intravenous and oral administration. After intravenous administration of KRโ33028 (1, 5, 10 and 20mg/kg doses), the systemic clearance (__Cl__) was reduced and __AUC
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