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Dose-dependent pharmacokinetics of KR-31378, a new neuroprotective agent for ischaemia-reperfusion damage in dogs

✍ Scribed by Sun-O. Kim; Sang-H. Kwak; Byung H. Lee; Dong-H. Lee; Hong Lim; Sung-E. Yoo; Hye J. Chung; Myung G. Lee


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
93 KB
Volume
25
Category
Article
ISSN
0142-2782

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Dose-dependent pharmacokinetics of a new
✍ Hee J. Kim; So H. Kim; Sun-O. Kim; Dong-H. Lee; Hong Lim; Sung-E. Yoo; Myung G. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 2 views

## Abstract The dose‐dependent pharmacokinetic parameters of a new neuroprotective agent for ischemia‐reperfusion damage, KR‐31378, were evaluated after intravenous and oral administration, 10, 20, and 50 mg/kg, to rats. After intravenous administration of 50 mg/kg, the dose‐normalized (10 mg/kg) A