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Dornase alfa improves lung function in CF


Book ID
120871768
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
1999
Weight
279 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Effect of smaller droplet size of dornas
✍ David E. Geller; Howard Eigen; Stanley B. Fiel; Andrew Clark; AndrΓ© P. Lamarre; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 71 KB πŸ‘ 1 views

Aerosolized recombinant human DNase (dornase alfa) reduces mucus viscoelasticity in vitro and improves pulmonary function in patients with cystic fibrosis (CF). We postulated that if dornase alfa could be delivered more peripherally to small airways in the lung in the form of smaller aerosol droplet