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Doris Teichler Zallen, To Test or Not To Test: A Guide to Genetic Screening and Risk

✍ Scribed by Jennifer Geurts


Book ID
106413944
Publisher
Springer
Year
2009
Tongue
English
Weight
68 KB
Volume
19
Category
Article
ISSN
1059-7700

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## Abstract Pharmacogenetic research indicates a relationship between a polymorphism in the gene encoding uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) and irinotecan inactivation, in that degradation of SN‐38, the active metabolite of irinotecan, correlates inversely with the number of