We read with interest the article by Grevle and colleagues, 1 reporting in Norway an association between the variant allele A1 of the TaqI A restriction fragment length polymorphism (RFLP) located in the dopamine D2 receptor (DRD2) gene and Parkinson's disease (PD). Similar findings have been report
Dopamine receptor D2 intronic polymorphism in patients with Parkinson's disease
✍ Scribed by Pau Pastor; Esteban Muñoz; Victor Obach; Marı́a José Martı́; Rafael Blesa; Rafael Oliva; Eduardo Tolosa
- Book ID
- 117478010
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 85 KB
- Volume
- 273
- Category
- Article
- ISSN
- 0304-3940
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📜 SIMILAR VOLUMES
## Abstract In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significa
## Abstract Genes encoding proteins involved in dopaminergic transmission are potential candidate genes for the induction of somnolence in Parkinson's disease (PD) because dopaminergic agents have been shown to be associated with sudden onset of sleep (SOS) in PD. We conducted an association study