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Dopamine levels in platelets and plasma of heroin plus cocaine addicts are increased

✍ Scribed by C.A. Fontes Ribeiro; T.R.A. Macedo; P. Tavares; M.T. Morgadinho; M.A.V. Abreu; P.P. Cunha; M.T. Nunes Vicente; L. Rodrigues; M.L. Keating

Book ID
119179733
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
145 KB
Volume
31
Category
Article
ISSN
1043-6618

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The density of platelet c~z-adrenoceptors, quantified by means of the binding of [3H]clonidine, and the aggregation response induced by adrenaline, was investigated in ten heroin addicts. The number of binding sites for [3H]clonidine was significantly increased during heroin abuse. Concomitantly, th