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Dopamine depletion increases in vivo [11C]DTBZ binding in awake rat brain

โœ Scribed by Michael R. Kilbourn; E.R. Butch; T. Desmond; P. Sherman; K.A. Frey


Book ID
118491221
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
58 KB
Volume
41
Category
Article
ISSN
1053-8119

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Positron emission tomography was used to examine the in vivo binding of [ 11 C]raclopride to D 2 -dopamine (DA) receptors in the striatum of two Cynomolgus monkeys after a single dose of reserpine (1 mg/kg, i.v.). A Scatchard procedure was repeated five times to follow D 2 receptor density and appar