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Dopamine D3 Receptor Mutant Mice Exhibit Increased Behavioral Sensitivity to Concurrent Stimulation of D1 and D2 Receptors

โœ Scribed by Ming Xu; Timothy E Koeltzow; Giovanni Tirado Santiago; Rosario Moratalla; Donald C Cooper; Xiu-Ti Hu; Norman M White; Ann M Graybiel; Francis J White; Susumu Tonegawa


Book ID
117607445
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
407 KB
Volume
19
Category
Article
ISSN
0896-6273

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Dopamine D3 receptor mutant and wild-typ
โœ Ming Xu; Timothy E. Koeltzow; Donald C. Cooper; Susumu Tonegawa; Francis J. Whit ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 66 KB

Previous studies using a variety of drugs with different affinities for the dopamine (DA) D3 receptor suggested that this receptor is involved in regulating motor activity and hypothermia. However, the in vivo selectivity of many of these compounds has been repeatedly questioned. To examine the prec