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Dominant-negative p53 mutations in rheumatoid arthritis

✍ Scribed by Zuoning Han; David L. Boyle; Yan Shi; Douglas R. Green; Gary S. Firestein


Book ID
101388525
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
173 KB
Volume
42
Category
Article
ISSN
0004-3591

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## Abstract In addition to the loss of function, mutant p53 can possess a dominant‐negative effect on wild‐type p53 and may also exert gain‐of‐function activity. It is not clear whether the functional status of __p53__ mutation contributes to differences in outcome in endometrial cancer. We collect