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Does the mitochondrial genome play a role in the etiology of Alzheimer’s disease?

✍ Scribed by Joanna L. Elson; Corinna Herrnstadt; Gwen Preston; Leon Thal; Christopher M. Morris; J. A. Edwardson; M. Flint Beal; Douglass M. Turnbull; Neil Howell

Publisher
Springer
Year
2006
Tongue
English
Weight
312 KB
Volume
119
Category
Article
ISSN
0340-6717

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## Abstract Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to t