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Does the gerbil model mimic human iron overload?

โœ Scribed by Lana Kaiser; John M. Davis; Kenneth A. Schwartz


Book ID
114053429
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
64 KB
Volume
141
Category
Article
ISSN
1532-6543

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Gerbils administered iron dextran are the only animal species which have been shown to develop hemochromatosis of the liver and heart in the same manner as transfusion dependent homozygous thalassemics. The iron chelating hydroxypyridinone, CP94, has been administered prophylactically to iron overlo